CONSECRATE v.
To make, or declare to be, sacred; to appropriate to sacred uses; to set apart, dedicate, or devote, to the service or worship of God; as, to consecrate a church; to give (one's self) unreservedly, as to the service of God. One day in the week is . . . consecrated to a holy rest. Sharp.
DE- n.
ative and opposite in derange, deform, destroy, etc. It is intensive in deprave, despoil, declare, desolate, etc.