BANE

That which destroys life, esp. poison of a deadly quality. [Obs. except in combination, as in ratsbane, henbane, etc.]

Destruction; death. [Obs.] The cup of deception spiced and tempered to their bane. Milton.

Any cause of ruin, or lasting injury; harm; woe. Money, thou bane of bliss, and source of woe. Herbert.

A disease in sheep, commonly termed the rot.

To be the bane of; to ruin. [Obs.] Fuller.